Study: Use of rhBMP in cervical spine associated with likelihood of complications

http://www.healio.com/spine-surgery/cervical/news/online/%7Bfea735f0-5099-42e1-aa83-4f005657e73a%7D/study-use-of-rhbmp-in-cervical-spine-associated-with-likelihood-of-complications

Study: Use of rhBMP in cervical spine associated with likelihood of complications

Jain A. J Bone Joint Surg Am. 2014; doi:10.2106/JBJS.M.00666

• May 7, 2014

Despite an FDA notification in 2008 of its possible adverse effects in spine surgery, the use of recombinant human bone morphogenetic protein or rhBMP in cervical spine surgery has continued. In this recent study, researchers found rhBMP use was associated with a significantly higher likelihood of cervical-spine-specific complications.

“Despite these shortcomings, our study provides a comprehensive overview of patient, surgical, and institutional factors associated with rhBMP use and we reported cervical-spine-specific in-hospital complications that may develop as sequelae of rhBMP use. A thorough understanding of these factors and complications is essential to enable surgeons to weigh the risks of rhBMP use against its benefits,” Jain and colleagues. – by Robert Linnehan

Disclosures: None of the authors received payments or services, either directly or indirectly, from a third party in support of any aspect of this work. One or more of the authors, or his or her institution, has had a financial relationship, in the 36 months prior to submission of this work, with an entity in the biomedical arena that could be perceived to influence or have the potential to influence what is written in this work.